Developing and applying sound science to the environmental risk assessment (ERA) of biotechnologies is crucial for safely realizing their contributions to human health and sustainable production of food, fuel, and fiber. Whether it be through improving systematic approaches to inform understanding of plausible risks associated with the use of gene drive strategies or working to maximize the value of data, the ILSI Research Foundation continues its longstanding commitment to serve as a scientific resource for governments, academic institutions, and private sector organizations.
Collaborators & Partners
USDA Foreign Agricultural Service, International Food Policy Research Institute (IFPRI), Foundation for the National Institutes of Health (FNIH), New Partnership for African Development (NEPAD), Common Market for Eastern and Southern Africa (COMESA), Organisation for Economic Co-operation and Development (OECD), and the Government of Australia
The ILSI Research Foundation's active programs related to environmental risk assessment (ERA) include:
Confined field trials (CFTs) are conducted to inform environmental risk assessments that are required by regulatory authorities before genetically engineered crops can be approved and released for cultivation. Many countries expect CFTs to be conducted as a matter of course, even if satisfactory data are already
available from trials conducted elsewhere. The primary variable that differentiates CFT locations is agroclimate, which means that data from trials cultivated in like agroclimates should be considered relevant and sufficient to satisfy regulatory requirements, irrespective of the country where the CFTs are conducted.
According to the World Health Organization’s 2017 World Malaria Report, an estimated 216 million cases of malaria occurred worldwide in 2016, with 90% of this total concentrated in the African region. Alarmingly, and despite an increased public health focus on the elimination of malaria, it is becoming clear that many countries will not be able to achieve this goal without considering novel management approaches. One control strategy in the early stages of development is the use of gene drive mechanisms to suppress or replace vector mosquito populations.
The ILSI Research Foundation's concluded projects in the area of environmental risk assessment include:
The ILSI Research Foundation’s Center for Environmental Risk Assessment, ILSI Brasil and ArgenBio convened a workshop for regulators, risk assessors and scientists from public and private sector organizations from August 12-15 in Buenos Aires, Argentina.
This summary publication captures the findings from four African consultations organized by the New Partnership for Africa’s Development (NEPAD) to identify risk hypotheses and data needs for future environmental risk assessment of gene drives in the mosquito Anopheles gambiae.
Volume 8 of the series Safety Assessment of Transgenic Organisms in the Environment contains the first OECD biosafety consensus document to deal with the biology of an insect, the mosquito Aedes aegypti.
Surrogate species have a long history of use in research and regulatory settings to understand the potentially harmful effects of toxic substances including pesticides.
RNA interference, or RNAi, refers to a set of biological processes that make use of conserved cellular machinery to silence genes.
This article is the Spanish translation of “Proposed Criteria for Identifying GE Crop Plants That Pose a Low or Negligible Risk to the Environment Under Conditions of Low-Level Presence in Seed,” which appeared in Transgenic Research.